The international policy landscape of responsible business conduct (RBC) is shifting towards binding, legal requirements for businesses. Emerging regulations on RBC due diligence will impact the way public buyers interact with global supply chains. In this context, governments should lead by example in promoting RBC in their own commercial activities, including public procurement. This paper analyses the implications of RBC due diligence regulation for government procurement. It analyses diverse effects for public administrations and explores potential effects of policy coherence on global supply chains.