Test No. 474: Mammalian Erythrocyte Micronucleus Test

DOI:https://dx.doi.org/10.1787/9789264264762-en

The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone marrow and/or peripheral blood cells of animals, usually rodents (mice or rats).



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