Test No. 456: H295R Steroidogenesis Assay

DOI:http://dx.doi.org/10.1787/9789264122642-en

This Test Guideline describes an in vitro screen for chemical effects on steroidogenesis, specifically the production of 17ß-estradiol (E2) and testosterone (T). The human H295R adreno-carcinoma cell line, used for the assay, expresses genes that ...



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